We know HDL as a 'Good Guy', but like many of us who are good for some and not so good for others - competing risks?? attenuating factors??? - a new research confirms that high levels of HDL are linked to increased breast cancer risks and to enhanced cancer aggressiveness . A team of researchers led by Philippe Frank, a cancer biologist in the Department of Biochemistry and Molecular Biology at Thomas Jefferson University, has shown that an HDL receptor found on breast cancer cells may be responsible for this effect. This study brings in a new target pathway for preventing tumor progression. It may well be the beginning for more on development of new drugs targeting SR-BI or cholesterol metabolism and eventually preventing tumor progression.
Source:Thomas Jefferson University
Category: Funding longer lives: Health/medicine